Cisco ISR4221/K9
ISR 4221 (2GE2NIM4G FLASH4G DRA

Key facts
Overview
CISCO ISR 4221 (2GE2NIM4G FLASH4G DRA
Cisco® 4000 Family Integrated Services Routers (ISRs) form an Software Defined WAN platform that delivers the performance, security, and convergence capabilities that today's branch offices need.
Product Overview
The Cisco 4000 Family Integrated Services Router (ISR) revolutionizes WAN communications in the enterprise branch. With new levels of built-in intelligent network capabilities and convergence, it specifically addresses the growing need for application-aware networking in distributed enterprise sites. These locations tend to have lean IT resources. But they often also have a growing need for direct communication with both private data centers and public clouds across diverse links, including Multiprotocol Label Switching (MPLS) VPNs and the Internet.
The Cisco 4000 Family contains the following platforms: the 4461, 4451, 4431, 4351, 4331, 4321 and 4221 ISRs.
Features and Benefits
Cisco 4000 Family ISRs provide you with Cisco® Software Defined WAN (SDWAN) software features and a converged branch infrastructure. Along with superior throughput, these capabilities form the building blocks of next-generation branch-office WAN solutions.
Cisco Software Defined WAN
Cisco SDWAN is a set of intelligent software services that allow you to reliably and securely connect users, devices, and branch office locations across a diverse set of WAN transport links. SDWAN-enabled routers like the ISR 4000 dynamically route traffic across the "best" link based on up-to-the-minute application and network conditions for great application experiences. You get tight control over application performance, bandwidth usage, data privacy, and availability of your WAN links - control that you need as your branches conduct greater volumes of mission-critical business.
Cisco Converged Branch Infrastructure
The Cisco 4000 Series ISRs consolidate many must-have IT functions, including network, compute, and storage resources. The high-performance, integrated routers run multiple concurrent services, including encryption, traffic management, and WAN optimization, without slowing your data throughput. And you can activate new services on demand through a simple licensing change.
Cisco Intent Based Networking and Digital Network Architecture (Cisco DNA)
The last few years has seen a rapid transformation and adoption of digital technologies. This puts pressure on the on the Network teams supporting this changing infrastructure - especially when provisioning, managing, monitoring and troubleshooting these diverse devices. Additionally innovations such as Software Defined WAN (SDWAN), Network Function Virtualization (NFV), Open APIs and Cloud Management show great promise in transforming Organizations IT networks. This transformation raises further questions and challenges for the IT teams.
Cisco DNA relies on intent-based networking, a revolutionary approach in networking that helps organizations automate, simplify, and secure the network.
- With Gigabit Ethernet, retrieve up to 10x faster than standard Ethernet connectivity and provides high-performance
- Rack-mountable feature for convenient and safe installation of the router
- Management capability provides control over the router's setup and configuration
- With 1000Base-T technology, get up to 1000 mbps data transfer rate over twisted pair cable
- Create a wired network with all the PCs connected with this router and share your Internet connection as well as files while checking emails
Specifications
General
- Total Number of Expansion Slots
- 3.0
- Product Type
- Router
Manufacturer Website Address
- Manufacturer
- Cisco Systems, Inc
- Product Model
- 4221
- Product Name
- 4221 Router
- Product Series
- 4000
- Brand Name
- Cisco
- Compatible Rack Unit
- 1U
- Network Technology
- 1000Base-T
- Ethernet Technology
- Gigabit Ethernet
- Number of Network (RJ-45) Ports
- 2
- Management Port
- Yes
- Total Number of Ports
- 2
Reference price history
Recorded reference and list prices over time. Not Prology selling prices.
- Latest
- AUD 4,409.04≈ USD 3,068
- Oct 2026
- Lowest recorded
- AUD 4,409.04≈ USD 3,068
- Highest recorded
- AUD 4,409.04≈ USD 3,068
- Recorded
- 2026
- 1 price point
- RRP
- Prology AU
- Prology US
- List price
Buy or sell Cisco ISR4221/K9
Buying Cisco routers
Prology stocks the Cisco ISR4221/K9 from USD 298 on Prology AU and Prology US. Need more than one, or a different condition? Request a quote for volume pricing.
Selling Cisco routers
Have a spare or decommissioned ISR4221/K9? Prology buys used and surplus Cisco routers — single units or whole lots — and replies with an offer within 1 business day. Sell your ISR4221/K9.
- What is the Cisco ISR4221/K9?
- The Cisco ISR4221/K9 is a Cisco router – ISR 4221 (2GE2NIM4G FLASH4G DRA.
- How much does the Cisco ISR4221/K9 cost?
- The reference price on record is AUD 4,409.04 (Oct 2026). It is a reference figure, not a selling price — the live price is on the Prology store page.
- Where can I buy the Cisco ISR4221/K9?
- It is listed on Prology AU and Prology US. Use the “View on Prology” button above for live price, condition and stock, or request a quote for volume pricing.
- Can I sell a used Cisco ISR4221/K9?
- Yes. Prology buys used and surplus Cisco routers, including the ISR4221/K9. Get an offer — sell outright or trade in against your next order.
Request a quote for ISR4221/K9
Tell us the quantity and condition you need. Prology replies with a firm price and lead time within 1 business day.